What is Sesamin?
Sesamin is a naturally occurring lignan that is present in pure sesame
oil. For your information, a lignan is broadly considered an
antioxidant that is present in unfiltered and unrefined seeds of
sesame, pumpkin and flax as well as many other foods. Besides being a
strong antioxidant, sesamin has shown great promise as a lipid oxidizer
as well as to support anti-inflammatory action. Its main mechanism for
fatty acid oxidation (fat burning) is triggered by the enzyme known as
PPAR-alpha. PPAR-alpha (Peroxisome Proliferator-Activator Receptor
Alpha) is documented to exist in muscle, the liver and adipose tissue
(fat). Sesamin being a strong activator of this enzyme (PPAR-alpha) is
also involved in the beta-oxidation of fatty acids while simultaneously
decreasing lipogenesis, or in simple terms, the accretion of new fatty
acids. In other words, PPAR-alpha activation is directly correlated
with increasing fat burning in muscle tissue. Which is a good thing!!!
Sesamin and Insulin Sensitivity
Due to sesamin’s strong beta-oxidizing properties the substance can
also affect leptin levels and is documented to restore insulin
sensitivity in obese rodents. Insulin sensitivity is often impaired in
those whose body fat levels exceed 15% and above. In more simple terms,
by providing the necessary substrate; sesamin is believed to act as a
thermostat of sorts that can regulate leptin as well as insulin levels
from within the body keeping both in optimal balance.
Sesamin and Ketosis Sesamin is a welcomed addition for those who are on ketogenic diets
as it is known to increase ketone production thereby sparing lean
muscle tissue that is otherwise lost through amino acid conversion,
usually sacrificed to fuel the body on low carb diets. Ketogenesis (or
the formation of ketones) becomes a major fuel factor on low carb
(Atkins) diets as the brain cannot be driven by fatty acids and thereby
relies on glucose first..and ketones second. So essentially, without
Sesamin in your diet, the body will tap into muscle tissue for its
ketone needs since carbohydrates are obviously kept at bay (at least in
those who are on ketogenic or low carbohydrate diets).
In Closing Sesamin is an excellent addition to anybody’s workout regimen, not
only to increase fat burning, but also for its overall anti-oxidant and
nutrient partioning properties. Some of the later research even points
out that Sesamin shows great promise in the lowering of LDL (bad)
cholesterol while simultaneously increasing HDL (good) cholesterol
levels in humans.
Supplement Facts Serving Size: 1 Soft Gel Servings Per Container: 60
Amount Per Serving
% Daily Value*
Calories
9
Calories from Fat
9
Total Fat
1.0
g
2%
Saturated Fat
0.1
g
<1%
Trans Fat
0
g
Cholesterol
0 m
g
0%
Ultra Pure Sesame Oil (standardized for 500mg sesamin)
1000 m
g
†
Other Ingredients: Gelatin, Glycerin, Water,
FD&C Blue # 1, Titanium Dioxide
* Percent daily value based on a 2000 caloric diet.
† Daily value not established.
**These
statements have not been evaluated by the FDA. This product is not
intended to diagnose, treat, cure or prevent any disease.