Sesamin is a lignan that is found in sesame seeds. A lignan is a molecule
that combines with a receptor to activate that receptor, and create a response.
The receptor and lignan will then perform a function in the body. Sesamin
is a lignan for the Peroxisome Proliferator-ActivatorReceptor Alpha (PPARalpha).
The receptor is found in muscle, liver, and heart tissue and is involved in the
oxidation (burning) of fat. Activation of PPARalpha increases gene expression
of the fatty acid oxidation (burning) enzymes and decreases gene expression of lipogenic
(fat storing) enzymes. Sesamin has been shown to be a potent PPARalpha activator.
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