Sesamin is a lignan that is found in sesame seeds. A lignan is a molecule
that combines with a receptor to activate that receptor, and create a response.
The receptor and lignan will then perform a function in the body. Sesamin
is a lignan for the Peroxisome Proliferator-ActivatorReceptor Alpha (PPARalpha).
The receptor is found in muscle, liver, and heart tissue and is involved in the
oxidation (burning) of fat. Activation of PPARalpha increases gene expression
of the fatty acid oxidation (burning) enzymes and decreases gene expression of lipogenic
(fat storing) enzymes. Sesamin has been shown to be a potent PPARalpha activator.
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Sesamin is an excellent addition to anybody’s workout regimen, not only to increase fat burning, but also for its overall anti-oxidant and nutrient partioning properties. Some of the later research even points out that Sesamin shows great promise in the lowering of LDL (bad) cholesterol while simultaneously increasing HDL (good) cholesterol levels in humans.