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Cinnulin-PF: The Spice That's More Than Nice

By: Victor Lasato

Since 2000 B.C.E., cinnamon has been regarded as an important spice, vital in developing trade routes from India and china to the rest of the world.  It was even held in such high regard that cinnamon was a common gift to royalty, and is mentioned in The Bible (Exodus 30:23). In modern times, cinnamon bark has evolved from a flavorful spice to a medicinal herb with antioxidant and antimicrobial properties (1). However scientists knew there were still more secrets to unlock from the bark of this miraculous plant. Enter Cinnulin-PF, An aqueous extract of various species of the cinnamon plant (Cinnamomum verum or C. zeylanicum are two commonly used species), that have the capability to drastically improve the quality of life for billions of people around the world.

Cinnulin-PF is the trade name of one of the most innovative dietary supplements ever unveiled by medical science.  Cinnulin is not just another over-hyped proprietary mix of ingredients backed merely by fancy marketing. This supplement has been under development for over 20 years.  Still not convinced? Try this little fact on for size: Cinnulin was not developed by a supplement company, but by a leading scientist at the US Department of Agriculture, and a Chinese disease-prevention organization: The Beijing Tang-An Medical Co. (Tang-An Co. is also the current patent holder).

Cinnulin's water-extraction method avoids common pitfalls associated with other extraction procedures. For example, acid/base extracts strip away valuable plant phenols and the main active component in cinnamon, double-linked Type-A Polymers (2). Tinctures only dissolve the alcohol-soluble components of the plant such as volatile and essential oils. As it turns out, eating the equivalent, effective dose of whole cinnamon powder (roughly one gram) or consuming other types of cinnamon extracts can stimulate 3T3-L1 preadipocytes similar to how insulin can create adipogenesis. In other words: it can make you fat (3). Earlier studies with cinnamon extracts clearly show the spice's ability to act as an insulin mimetic, hence it's stimulation of adipocytes. However the US Department of Agriculture's cinnamon activist, Dr. Richard Anderson has been studying cinnamon's effects on human metabolism for the past 20 years. Various solvents such as methanol, ethanol, and ether demonstrated antioxidant and antimicrobial properties, but didn't have the desired effects on lipid oxidation and glucose metabolism. In 2003, working with Integrity Nutraceuticals International (INI) Anderson finally struck “brownish-red gold” with a water-extraction that dissolved the desired polymers (4).

The water-extraction technique developed by Anderson and INI provides a standardized 20:1 extract that has been shown in a double blind, placebo controlled study to improve glucose metabolism and regulation in skeletal muscle tissue (5). Other studies suggest Cinnulin can also improve blood flow and other cardiac functions, provide antioxidant protection, and improve lipid profiles (5). Although most studies were done with Type-II Diabetics, the potential for this breakthrough supplement to improve the quality of life for the general public is overwhelming. Studies done on non-diabetic rats being fed a hyper-caloric, high-fructose diet, show Cinnulin's ability to inhibit insulin resistance (6). In addition to being a great general health supplement, Cinnulin, like other insulin mimetic compounds, can play a vital role in ketogenic diets and carbo-loads. According to Anderson's studies as well as further research conducted by INI, the optimal dose of Cinnulin-PF is 250mg. per day (4).  Keep in mind, this is the recommendation for the original, patented, aqueous-extract of cinnamon sold under the registered trade name: Cinnulin-PF. Many products contain the patented ingredient, protected under patent #6,200,569.


 References:
1. Cinnamon. Wikipedia. Available: www.en.wikipedia.org/wiki/Cinnamon
2. New Study Shows Cinnamon Extract Lowers Blood Sugar Levels in People With Type 2 Diabetes. WLBT3 Online. Available: www.wlbt3.com/Global/story.asp?S=5095214.
3. Taher, M. Et. Al.  Cinnamtannin B1 activity on adipocytes formation. The Medical Journal of Malasia. 2004: May;59 B:97-8. Available: PubMed.
4. Khan, A. Et. Al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003 Dec;26(12):3215-8. Available: PubMed.
5. South, James. Cinnamon Lowers Blood Sugar and Blood Lipids. Vitamin Research Products. Available: www.vrp.com
6. Qin, B. Cinnamon extract prevents the insulin resistance induced by a high-fructose diet. Hormone and Metabolic Research. 2004 Feb;36(2):119-25.

Cinnulin Supplements Antioxidant and Antimicrobial Properties